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ViewAttendees 1

RC2 - Roller Coaster 2

Wednesday, November 13, 2024
10:45 AM – 12:15 PM MST
Location: Sonoran Sky Ballroom 1-4

Disclosure(s):
Fiona Glassman, PhD: No financial relationships to disclose
Jin Dong, PhD: AstraZeneca: Employment (Ongoing)
Lisl Shoda, PhD: No financial relationships to disclose
Fulya Akpinar Singh, PhD: No financial relationships to disclose
Colin W. Castleberry, PhD: Amgen: Employment (Ongoing), Ownership Interest (stocks, stock options, patent or other intellectual property or other ownership interest excluding diversified mutual funds) (Ongoing)
Suein Choi, MD., PhD.: No financial relationships to disclose

Presentations:

  • 10:50 AM – 11:05 AM MST
    Decoding complex drug-drug-renal disease interaction mediated by hepatic enzymes and transporters using PBPK approach

    Chair: Jin Dong, PhD – AstraZeneca

  • 11:05 AM – 11:20 AM MST
    Hitting the Sweet Spot: Mechanism-Based Modeling to Evaluate the Interplay of Liver Compound Exposure and Liver Toxicity to Identify Safe Dosing Regimens

    Speaker: Lisl Shoda, PhD (she/her/hers) – Simulations Plus Inc

  • 11:20 AM – 11:35 AM MST
    Validating QSP Models with Finesse: Elevating Performance through Biologically Anchored Precision

    Speaker: Fulya Akpinar Singh, PhD (she/her/hers) – Genmab

  • 11:35 AM – 11:50 AM MST
    Quantitative Systems Pharmacology Modeling to Inform Preclinical-to-Clinical Translation of T-cell Engager Programs

    Speaker: Colin W. Castleberry, PhD (he/him/his) – Amgen

  • 11:50 AM – 12:05 PM MST
    Integrated Microphysiological System and PBPK Modeling for Prediction of Human Diclofenac Pharmacokinetics

    Speaker: Suein Choi, MD., PhD. (she/her/hers) – Catholic university of Korea