Lead Large Molecule Platform - Principal Scientist
ESQlabs, Belgium
Wilbert de Witte is a Prinicipal Scientist and Large Molecule PBPK Platform lead at ESQlabs.
Before joining esqLABS, he worked at Ablynx NV, later Sanofi Ghent, on the preclinical and clinical development of NANOBODY® therapeutics. He developed several PBPK and PBPK-QSP models as well as traditional TMDD and PKPD models for mechanistic analysis of in vitro, in vivo, and clinical data. He accumulated in-depth knowledge on the behavior of large molecules in different modalities and with various target binding characteristics.
Wilbert de Witte obtained his Master’s degree in Bio-Pharmaceutical Sciences from Leiden University (the Netherlands). For his PhD thesis, he studied the impact of drug-target binding kinetics on in vivo drug action at Leiden University.
