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Alexander Kulesza, PhD (he/him/his)

Principal Scientist
Systems Pharmacology Lead, Rhone-Alpes, France

Dr. Alexander Kulesza is currently Principal Scientist and Lead of Systems Pharmacology at ESQlabs GmbH, Saterland, Germany operating out of Lyon, France. He is also affiliated with the University of Namur, Belgium. After completing his theoretical and computational chemistry Diplom at the Humboldt-University Berlin, he obtained his PhD from the Free University Berlin studying inorganic - biomolecular hybrid systems by ab-initio quantum chemistry methods and molecular dynamics. He then moved to Lyon, France focusing on integrating advanced molecular dynamics techniques like replica-exchange and Free-Energy methods to integrate gas-phase structural biology experiments data for elucidating structurally disordered proteins. Alexander then moved out of fundamental reasearch into drug development joining Novadiscovery (now Nova In silico) as Scientist, then team leader then executive manager and since then working on quantitative systems pharmacology modeling combined with physiologically based pharmacokinetics in inflammatory, immune, infectious, metabolic disorders and (immuno)oncology with a focus on model credibility assessment for potential regulatory applications.

Disclosure(s): ABLATOM SAS: Ownership Interest (stocks, stock options, patent or other intellectual property or other ownership interest excluding diversified mutual funds) (Ongoing); CreativeQuantum GmbH: Ownership Interest (stocks, stock options, patent or other intellectual property or other ownership interest excluding diversified mutual funds) (Ongoing); ESQlabs GmbH: Employment (Ongoing)

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