Scientific Director, Oncology & Immuno-Oncology Quantitative Systems Pharmacology
InSysBio CY, Cyprus
Oleg Demin Jr is the Scientific Director of QSP Modeling in Oncology & Immuno-Oncology at InSysBio CY. He has over 10 years of experience in the application of mechanistic and quantitative systems pharmacology modeling to support drug R&D in various diseases and therapeutic areas, including oncology, immuno-oncology, immunology, type 2 diabetes, HCV, Alzheimer's disease, gout, celiac disease, and others. Since 2015, he has focused exclusively on oncology and immuno-oncology, including both solid tumors (melanoma, NSCLC) and hematological malignancies (AML, ALL, NHL). His current research interests include engineered cell therapies (CAR-T, TCR-T, CAR-NK, etc.), T-cell and NK-cell engagers, ADC, checkpoint inhibitors, and multispecific therapeutic antibodies.