C5B - The Practical Bayesian: How Bayesian Methodology is Incorporated into Clinical Drug Development

Chair(s)

• 

  Jiawei Zhou, PhD (she/her/hers)

  Manager, Pharmacometrics & Systems Pharmacology
  Pfizer, Inc.
  Greenville, South Carolina, United States
• 

  Luke Fostvedt, PhD

  Director, Pharmacometrics & Systems Pharmacology
  Pfizer, Inc.
  tempe, Arizona, United States

Speaker(s)

• 

  Timothy Waterhouse, PhD (he/him/his)

  Principal Scientist II
  Metrum Research Group, United States

  PDF Slides
• RS

  Ralph Smith, PhD

  Distinguished University Professor, Professor of Mathematics
  North Carolina State University, United States

  PDF Slides
• 

  Nastya Kassir, PharmD, PhD, FCP (she/her/hers)

  Senior Director & Distinguished Scientist
  Genentech
  San Francisco, California, United States

  PDF Slides

Presentations:

• 1:45 PM – 2:15 PM MST

  Hybrid Approaches in Pharmacometric Modeling: Integrating Maximum Likelihood and Bayesian Estimation
  

  Speaker: Timothy Waterhouse, PhD (he/him/his) – Metrum Research Group
• 2:15 PM – 2:45 PM MST

  Parameter Selection and Uncertainty Quantification Techniques for Pharmacokinetic Models
  

  Speaker: Ralph Smith, PhD – North Carolina State University
• 2:45 PM – 3:15 PM MST

  Applying Bayesian Methods for Dose Optimization in Pediatric Oncology: Leveraging from Adult Population Pharmacokinetics
  

  Speaker: Nastya Kassir, PharmD, PhD, FCP (she/her/hers) – Genentech