T3 - Trainee Tutorial: Minimal PBPK Modeling: Tutorial and Applications

Thursday, November 14, 2024

9:00 AM – 12:00 PM MST

Location: Palms 3 CD

Co-Chair(s)

Sean McCann (he/him/his)

Graduate Research Assistant
University of North Carolina
Flushing, Michigan, United States
Yuhan Long, BS, BSChE (he/him/his)

Graduate Student
University of Minnesota, Minnesota, United States

Speaker(s)

Yanguang Cao, PhD (he/him/his)

Associate Professor
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, United States
XL

Xiaonan Li, PhD (she/her/hers)

Sr. Clinical Pharmacologist
Takeda Pharmaceuticals
Dongfen Yuan, PhD

Associate Director
Janssen Research & Development
Edmond, Oklahoma, United States

Disclosure(s):

Sean McCann: No financial relationships to disclose

Yuhan Long, BS, BSChE: No financial relationships to disclose

Yanguang Cao, PhD: No financial relationships to disclose

Xiaonan Li, PhD: No financial relationships to disclose

Dongfen Yuan, PhD: Janssen Research & Development: Employment (Ongoing), Ownership Interest (stocks, stock options, patent or other intellectual property or other ownership interest excluding diversified mutual funds) (Ongoing)

Presentations:

9:00 AM – 9:30 AM MST

Introduction: Minimal PBPK Modeling: Tutorial and Applications
Speaker: Yanguang Cao, PhD (he/him/his) – University of North Carolina at Chapel Hill
9:30 AM – 10:15 AM MST

Small Molecule Minimal PBPK Models and Classic Hepatic Clearance Concept
Speaker: Xiaonan Li, PhD (she/her/hers) – Takeda Pharmaceuticals
10:45 AM – 11:15 AM MST

Large Molecule Minimal PBPK Models and FcRn Interactions
Speaker: Dongfen Yuan, PhD – Janssen Research & Development
11:15 AM – 12:00 PM MST

Trainee Tutorial: Q&A