Antoine Pitoy, PhD student: Association Nationale de la Recherche et de la Technologie: Grant/Research Support (Ongoing); Sanofi: Employment (Ongoing)
A simulation study to assess the ability of nonlinear joint models, built from phase I and II clinical trial data, to earlier estimate the final outcome of a Phase III clinical trial, in an interim analysis context. - Application of the proposed approach to estimate the outcome of the phase III ICARIA-MM trial data using a joint model approach, in a retrospective interim analysis.